The Schultz-Dale reaction of the depolarized guinea-pig uterus

Mechanism of the Schultz-Dale Reaction in the Denervated Diaphragmatic Muscle of the Guinea Pig

The mechanism of the contractions elicited by specific antigens in immunologically sensitized muscle tissue (Schultz-Dale responses) has been investigated on single fibers of denervated guinea pig hemidiaphragms. This preparation can be either actively or passively allergized, showing Schultz-Dale responses similar to those of visceral muscle. Specific antigens were applied with an electrically...

Adsorption of antibody in vitro and magnitude of the Schultz-Dale reaction of guinea-pig ileum.

Studies show that the adsorption of rabbit antiovalbumin-I(131) on guinea-pig ileum conforms to a Langmuirian isotherm, and that the physiological response to challenge with antigen depends upon the amount of antibody bound to the tissue.

Some observations on the feeding of the guinea pig

Salbutamol affects body composition of the guinea pig

Calcium and the contractile effect of carbachol in the depolarized guinea-pig taenia caecum.

Carbachol (10-8-10-3 M) caused a phasic contraction in the guinea-pig taenia caecum suspended in the Ca-free, K-Tyrode solution. The action of carba chol was concentration-related and was completely antagonized by atropine (10-6 g/ml). The capacity to contract in the absence of external Ca was removed by short term exposure to a high concentration of carbachol (...